Prostate Cancer Risk Factors: Age, Family History, etc.


Various epidemiological studies have indicated a number of factors that can predispose to prostate cancer.

Following is a list of prostate cancer risk factors:

prostate cancer risk factors infographic

Prostate Cancer Risk Factors:

  1. Age: Older age men are generally at increased risk of developing prostate cancer. About 60% of all the incidence of prostate cancer is observed in men older than 65 years of age.
  2. Family history: Individuals with a history of prostate cancer in close relatives are considered to be at increased risk of developing prostate cancer.
  3. Genetic alterations: Some inherited genetic alterations have been reported to be associated with a high risk of prostate cancer, e.g., Lynch syndrome or hereditary non-polyposis colorectal cancer (HNPCC, generally caused by mutation in the MLH1 or MSH2 gene), mutations in RNASELMSR1HOXB13, and BRCA2 genes, etc.
  4. Race/ethnicity: African-American and Caribbean men are generally at higher risk of developing and dying of prostate cancer.
  5. Overweight or obese males are at higher risk of developing an aggressive form of prostate cancer.
  6. Diet: It has been reported that a diet rich in red meat, fats, dairy foods, and calcium may increase the risk of prostate cancer, while an adequate consumption of vegetables and antioxidants such as vitamin E and selenium may reduce the risk of prostate cancer.

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To further understand the disease in a better way, have a look at the video below where CancerBro meets Mr. Poppy who has recently being diagnosed with prostate cancer.

CancerBro asks Mr. Poppy several important questions related to his disease from early symptoms which lead him to contact an oncologist, to various other risk factors related to prostate cancer.

Video Transcript:

CancerBro – Hi Mr. Poppy, how are you feeling today? Can I ask you a few questions related to your disease?

Mr. Poppy – I am feeling better now. Yes CancerBro, I will be happy to answer your questions please go ahead.

CancerBro: Mr. Poppy, how old are you and where are you from?

Mr. Poppy: I am 65 years old and I am from USA.

CancerBro: Tell me what were your initial complaints for which you consulted the doctor?

Mr. Poppy: For last one and half month I was having difficulty in passing urine. I had to go repeatedly for urination even during night, also the urine stream was not proper. Sometimes, I noticed blood in urine. Recently, I had difficulty in erection and also back pain.

CancerBro: Please tell me something about your diet and activity schedule.

Mr. Poppy: I used to eat red meat and fatty food, and due to my hectic work schedule, I rarely did any exercise.

CancerBro: Did anyone else in your family has been diagnosed with prostate cancer previously?

Mr. Poppy: Yes my father also had a prostate cancer.

CancerBro: Okay Mr. Poppy, thank you very much.

And in the following video, Cancerbro explains the various RISK FACTORS associated with prostate cancer.

Video Transcript:

– Prostate cancer is a disease of old age. More and more people are being diagnosed with the disease due to increasing life expectancy, by 90 years of age 50 to 60% of will have the disease.

– Western countries has the highest incidence of this disease, highest being in the African American.

– Asian migrated to the western countries have higher incidence than the native.

– Red meat and fatty foods, containing saturated fatty acids increase the risk of prostate cancer.

– Sedentary lifestyle with increasing obesity also increases the risk of prostate cancer.

– Regular physical activity decreases the mortality and improves outcome in patients with the disease.

– Number of people previously affected with the disease increases the risk in other family members.

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